Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Inflammation
ADR ID BADD_A05823
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.05      Inflammations
08.01.05.007      Inflammation
Description A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code 10061218
MeSH ID D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Interleukin-1 alphaP01583T16340
Interleukin-10P29456Not Available
Interleukin-6P05231T32578
Interleukin-8P10145T22658
Nuclear receptor subfamily 4 group A member 3Q92570T93949
Retinol-binding protein 1P09455Not Available
Tumor necrosis factorP01375T20178
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00479Cladribine--
BADD_D00480Clarithromycin0.003290%
BADD_D00483Clindamycin--
BADD_D00487Clindamycin phosphate--
BADD_D00501Clonazepam--
BADD_D00504Clopidogrel0.000294%
BADD_D00511Clozapine0.067258%
BADD_D00528Conjugated estrogens0.001037%
BADD_D00535Crizotinib0.003197%
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine0.001817%
BADD_D00560Cytarabine0.000799%
BADD_D00561Cytarabine hydrochloride--
BADD_D00564Dabigatran etexilate--
BADD_D00566Dabrafenib0.000799%
BADD_D00572Dalbavancin0.000213%
BADD_D00574Dalfampridine--
BADD_D00581Daptomycin0.000213%
BADD_D00586Darunavir--
BADD_D00589Dasatinib0.001865%
BADD_D00594Deferasirox0.026240%
BADD_D00599Degarelix--
BADD_D00603Delavirdine--
BADD_D00605Demeclocycline--
BADD_D00606Demeclocycline hydrochloride--
BADD_D00609Deoxycholic acid0.000879%
BADD_D00615Desloratadine0.003965%
BADD_D00628Dexlansoprazole--
BADD_D00648Diazepam0.000427%
BADD_D00653Diclofenac0.000711%
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